Liver fatty acid-binding protein as a sensitive serum marker of acute hepatocellular damage in liver transplant recipients.
نویسندگان
چکیده
Marker of Acute Hepatocellular Damage in Liver Transplant Recipients, Maurice M.A.L. Pelsers, Alireza Morovat, Graeme J.M. Alexander, Wim T. Hermens, Andrew K. Trull, and Jan F.C. Glatz ( Department of Physiology, 2 Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands; Departments of 3 Clinical Biochemistry and 4 Medicine, Addenbrooke’s Hospital, Cambridge CB2 2QQ, United Kingdom; * author for correspondence: fax 31-43-3884166, e-mail [email protected])
منابع مشابه
Rapid Diagnosis of acute kidney injury (AKI) associated with cardiac surgery, using the liver type fatty acid binding protein (L-FABP) biomarker
Abstract Background and objectives: cardiac surgery is often associated with acute kidney injury (AKI). Nowadays, AKI is typically diagnosed by an increase in serum creatinine, which is a delayed and unreliable biomarker. Recent studies recommended using the liver type fatty acid binding protein (L-FABP) as an early biomarker. Material and Methods: The urine samples of 18 adult patients undergo...
متن کاملInterleukin-17 Gene Expression and Serum Levels in Acute Rejected and non-Rejected Liver Transplant Patients
Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute rejection. Methods: Ninety seven adult liver transplant patients who enrolled in this cross sec...
متن کاملEffects of feed restriction and dietary fat type on mRNA expression of liver fatty acid-binding protein (L-FABP) in broilers
Background: Liver fatty acid-binding protein (L-FABP) is the main cytosolic binding site for long chain fatty acids in hepatocytes. FABPs enhance the uptake of fatty acids into the cell by increasing their concentration due to decreasing concentration of unbound fatty acids inside the cell. Objectives: The aim of this study was to evaluate the effects of dietary unsaturated to saturated fatty a...
متن کاملLiver Type Fatty Acid Binding Protein (L-FABP): A Marker of Contrast Induced -Acute Kidney Injury
Background: Urinary Liver type fatty acid binding protein (L-FABP) is an early biomarker for renal damage. A few studies have been published analyzing the potential use of urinary Liver type fatty acid binding protein (L-FABP) as a biomarker for acute kidney injury. However no study has been done related to Acute Kidney Injury associated with contrast administration. Aim: To search for new mark...
متن کاملسطح سیتوکراتین 18، فعالیت آنزیم پاراکسوناز و پروفایل لیپیدی در بیماران کبد چرب غیرالکلی در ایران
Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease is increasing in adults and children worldwide. Obesity, insulin resistance or diabetes type II, hyperlipidemia and hypertriglyceridemia plays a major role in the epidemiology of this disease. Cytokeratin 18 (CK-18) the major intermediate filament protein in the liver is a marker of increased hepatocyte apoptosis. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical chemistry
دوره 48 11 شماره
صفحات -
تاریخ انتشار 2002